姓名 | 混旭 | |
性别 | 男 | |
年龄 | 42 | |
职称 | 教授 | |
学历(学位) | 博士 | |
所属院系 | 青岛科技大学/化学与分子工程学院 | |
导师类别 | 硕士生导师 | |
招生专业 | 分析化学、应用化学及相关专业 | |
研究方向 | 化学与生物传感器;表面修饰与性能;功能性材料 | |
联系方式 | hunxu@sohu.com;13589261357 | |
个人简历 | ||
博士,教授,2004年~2008年任教于西安工业大学,现任教于青岛科技大学化学与分子工程学院化学教研室。 一直从事化学与生物传感器与表面修饰与性能等方面的研究,每年指导硕士研究生6-9名。发表SCI论文60余篇,其中影响因子3.0以上26篇,5.0以上17篇,1区论文22篇。申请专利36项,授权专利23项,主持国家级项目等10项,获中国分析测试协会三等奖1项,山东省研究生优秀科技创新成果奖1项,山东省高等学校优秀科研成果奖1项,2016年度山东化工精英人物称号,青岛市科学技术奖三等奖1项,2008-2013年度高水平科技论文突出贡献奖1项,校级优秀研究生指导教师奖2项。 科研项目 1. 国家自然科学基金“基于目标诱导链释放的高灵敏度信号放大技术的构建及食品中毒素检测研究”(21275085),项目负责人 2. 国家自然科学基金“生物条形码标记化学发光免疫分析法检测植物激素的研究” (21005045),项目负责人 3. 国家自然科学基金“基于目标诱导链释放的高灵敏度信号放大技术的构建及食品中毒素检测研究” (21275085),项目负责人 4. 青岛市科技局“海洋赤潮毒素的毛细管电泳电化学在线快速检测新技术和新仪器” (09-1-3-45-jch),项目负责人 5. 省教育厅专项科研基金“K3Fe(CN)6化学发光体系在药物CE-CL中的应用研究” (05jk218),项目负责人 6. 国家重点实验室开放课题“基于切口核酸内切酶酶切信号放大技术的食品中毒素高灵敏度检测方法的研究”(SKLF-KF-201112),项目负责人 7. 启动基金(09-1-3-45-jch),项目负责人 8. 国家海洋局海洋生物活性物质与现代分析技术重点实验室开放课题(MBSMAT-2015-04),项目负责人 9. 省教育厅科技计划项目“沿海贝类腹泻性贝毒毛细管电泳电化学检测试剂盒的研制”(J09LB09) 10. 省教育厅专项科研基金“聚偏二氟乙烯及其共聚物化学改性及性能研究”(06jk596) 代表性论文 1. Xu HunYan Meng, Shanshan Wang, Hui Zhang, Xiliang Luo Mismatched catalytic hairpin assembly couplinghydroxylamine-O-sulfonic acid as oxide for DNA assay Sensors and Actuators B 254(2018)347–353(IF=4.7) 2. Xu Hun, Yan Meng, Shiyu Wang, Zhenghua Mei, Xiliang Luo Concatenated logic gates by amplified chemiluminescence ofhemin/G-Quadruplex DNAzyme based on a nonlinear hybridizationchain reaction Sensors and Actuators B 246(2017)734–739(IF=4.7) 3. Xu Hun,ShanshanWang, Shuyu Mei, Hongqing Qin, Hui Zhang, Xiliang Luo Photoelectrochemical dopamine sensor based on a gold electrode modified with SnSe nanosheets Microchim Acta184(2017), 3333–3338(IF=4.8) 4. Xu Hun,Shanshan Wang, Shiyu Wang, Jikuan Zhao, Xiliang Luo A photoelectrochemical sensor for ultrasensitive dopamine detection based on single-layer NanoMoS2 modified gold electrode Sensors and Actuators B 249(2017)83–89(IF=4.7) 5. Xu HunBingru Liu Yan Meng Ultrasensitive chemiluminescence assay for the lung cancer biomarker cytokeratin 21-1 via a dual amplification scheme based on the use of encoded gold nanoparticles and a toehold-mediated strand displacement reaction Microchimica Acta 184(2017), 3953–3959(IF=4.8) 6. Yingxia Zong, Fang Liu, Yue Zhang, Tianrong Zhan, Yunhua He,Xu Hun Signal amplification technology based on entropy-driven molecularswitch for ultrasensitive electrochemical determination of DNA and Salmonella typhimurium Sensors and Actuators B 225(2016)420-427(IF=4.8) 7. Yan Meng,Xu Hun, Yue Zhang, Xiliang Luo Toehold-aided DNA recycling amplification using hemin and G-quadruplex reporter DNA on magnetic beads as tags for chemiluminescent determination of riboflavin Microchimica Acta, 2016, 183(11):1-7(IF=4.7) 8. Xu Hun,Guoliang Xie and Xiliang Luo Scaling up an electrochemical signal with a catalytic hairpin assembly coupling nanocatalyst label for DNA detection Chemical Communation,2015,51, 7100-7103(IF=6.7) 9. Xu Hun, Yaqiong Xu, Li Bai A chemiluminescence assay for L-histidine based on controlled DNAzyme catalytic reactions on magnetic microparticles Microchimica Acta,2015, 182:565–570(IF=3.8) 10. Xu Hun, YaqiongXu, Guoliang Xie and Xiliang Luo Aptamer biosensor for highly sensitive and selective detection of dopamine using ubiquitous personal glucose meters Sensors and Actuators B,2015, 209, 596–601(IF=3.8) 11. Yaqiong Xu,Xu Hun,Fang Liu, Xiaolong Wen and Xiliang Luo Aptamer biosensor for dopamine based on a gold electrode modified with carbon nanoparticles and thionine labeled gold nanoparticles as probe Microchimica Acta,2015, 182, 1797-1802(IF=3.8) 12. Xu Hun,Yaqiong Xu,and Xiliang Luo Peptide-based biosensor for the prostate-specific antigen using magnetic particle-bound invertase and a personal glucose meter for readout Microchim Acta,2015, 182:1669–1675 (IF=3.8) 13.Xu Hun,YaqiongXu, Chao Chen DNA-based hybridization chain reaction for signal amplification and ultrasensitive chemiluminescence detection of gibberellic acid Sensors and Actuators B,2014, 202: 594(IF=3.8) 14. Xu Hun,Wei Sun, Huanhuan Zhu, Feng Du, Fang Liu, Yaqiong Xu and Yun He Design of electrochemical detection of thiols based on the cleavage of the disulfide bond coupled with thionine modified gold nanoparticles-assisted amplification. Chemical Communation,2013,49: 9603 (IF=6.7) 15. Xu Hun,Fang Liu, Zhenhua Mei, Lifeng Ma, Zhouping Wang and Xiliang Luo Signal amplified strategy based on target-induced strand release couplingcleavage of nicking endonuclease for the ultrasensitive detection of ochratoxin A. Biosensors and Bioelectronics,2013, 39:145(IF=5.7) 16. Xu Hun,Liang Tiao and Zhujun Zhang Fluorescent nanoparticles for ovarian cancer imaging. CRC Press, Taylor & Francis Group.2012专著 17. Xu Hunand Zhouping Wang L-Argininamide biosensor based on S1 nuclease hydrolysis signal amplification. Microchim Acta,2012, 176: 209(IF=3.4) 18. Xu Hun Indole-3-acetic acid biosensor based on G-rich DNA labeled AuNPs as chemiluminescence probe coupling the DNA signal amplification Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy,2012, 95: 114(IF=1.9) 19. Pei Liu,Xu Hunand Hongqing Qing Dendrimer-based biosensor for chemiluminescent detection of DNA hybridization Microchim Acta,2011, 175: 201(IF=3.4) 20. Xu Hun,Huaichen Chen and Wei Wang A electrogenerated chemiluminescence biosensor for ramos cancer cell using DNA encapsulated Ru(bpy)3Cl2 as signal probe Biosensors and Bioelectronics,2011, 26: 3887(IF=5.4) 21. Xu Hun,Huaichen Chen and Wei Wang Design of ultrasensitive chemiluminescence detection of lysozyme in cancer cells based on nicking endonuclease signal amplification technology. Biosensors and Bioelectronics,2010,26(1): 248(IF=5.4) 22. Hua Zhong, Xi Lei,Xu Hunand Shusheng Zhang Design of one-to-one recognition triple Au nanoparticles DNA probe and its application in the electrochemical DNA biosensor. Chemical Communation,2009,47:6958(IF=5.3) 授权发明专利 2012102081466 基于纳米金和硫堇信号放大检测谷胱甘肽的方法 2012102081593目标诱导链释放和限制性内切酶酶切循环的信号放大技术建立及赭曲霉素A的检测 2013102539267一种双组份植物激素的同时测定方法 2014102742222一种测定三聚氰胺的电化学方法 2014102469659一种检测L-组氨酸的生物传感器的制备方法及其应用 2014102480751 一种检测基质金属蛋白酶-2的生物传感器的制备方法及其应用 2014102724313一种信号放大技术电化学传感器检测DNA的方法 2014102724811一种基于适体识别作用电化学测定多巴胺的方法 2015103367197 一种基于纳米粒子标记氧化还原循环检测多巴胺的方法 2013106558708 一种基于杂交链式反应信号放大技术测定赤霉素的方法 获奖 中国分析测试协会三等奖1项, 山东省研究生优秀科技创新成果奖1项, 山东省高等学校优秀科研成果奖1项, 2016年度山东化工精英人物称号, 青岛市科学技术奖三等奖1项, 2008-2013年度高水平科技论文突出贡献奖1项, 校级优秀研究生指导教师奖2项。 |