性别

   女

 出生年月

  1974.07

 职称

   教授

 学历（学位）

   博士

 所属院系

    化学与分子工程学院

 导师类别

     博导

 行政职务

   教育部重点实验室副主任

 招生专业

分析化学

 研究方向

   光电传感与生化分析

 联系方式

   15064250022  zhangxr7407@126.com

个人简历（包括近期科研项目）

学习研究经历、主要研究方向，取得主要成果、完成及承担的主要科研项目等。

于天津大学获学士和硕士学位，2003年毕业于中国海洋大学药物所获博士学位。研究内容涉电化学、化学发光、荧光及光致电化学等，近期主要包括激光共聚成像和拉曼成像研究，特别是细胞的成像研究。同时开展了新型功能化材料的研究如碳纳米管、石墨烯等。作为项目负责人承担国家自然科学基金三项：面上项目，65万元；青年-面上连续资助，80万元；青年基金，23万元。山东省重点研发项目一项，15万元；山东省中青年科学家奖励基金一项，6万元。中国海洋大学海洋药物教育部重点实验室开放基金，3万元。山东大学微生物技术国家重点实验室开放基金，2万元。获山东省科学技术自然科学二等奖一项（第二位），获山东省高校科研成果三等奖一项（第一位），获山东省高校科研成果一等奖两项（第二位）。近年作为第一作者或通讯作者在Chem. Sci., Anal. Chem., Chem. Commun.等国际著名学术期刊发表SCI论文20余篇，其中影响因子大于5.0的SCI论文20余篇。作为第一发明人授权国家发明专利两项。

近期发表主要文章：

1、Li   Zhao, Ruijiao Sun, Peng He, and Xiaoru Zhang* Ultrasensitive Detection   of Exosomes by Target-Triggered ThreeDimensional DNA Walking Machine and   Exonuclease III-Assisted Electrochemical Ratiometric Biosensing. Anal. Chem. 2019, 91,   14773-14779.

2、Xiaoru Zhang, Chao Liu, Yujiao Pei, Weiling   Song, and Shusheng Zhang, Preparation   of a Novel Raman Probe and Its Application in the Detection of Circulating   Tumor Cells and Exosomes, ACS Appl. Mater. Interfaces 2019, 11,   28671-28680.

3、Zhenzhu   Luan, Li Zhao, Chao Liu, Weiling Song, Peng He, Xiaoru Zhang*   Detection of casein kinase II by aggregation-induced emission, Talanta 201 (2019) 450–454.

4、Ying Li, Huixia Han, Yingdi Wu, Chuanfeng Yu, Chunnian Ren and   Xiaoru Zhang*, Telomere Elongation-Based DNA-Catalytic Amplification Strategy for Sensitive SERS Detection of Telomerase Activity,   Biosensors and Bioelectronics，2019, 142, 111543

5、  Xiaoru Zhang, Fengting Chen,   Xiaojie Song, Peng He, Shusheng Zhang, Proximity ligation detection of lectin   Concanavalin A and fluorescence imaging cancer cells using carbohydrate   functionalized DNA-silver nanocluster probes. Biosens. Bioelectron., 2018, 104, 27

6、  Ying Li, Fengting   Chen, Zhenzhu Luan, Xiaoru   Zhang*,   A versatile cathodic “signal-on” photoelectrochemical platform based on a   dual-signal amplification strategy, Biosens. Bioelectron.  2018, 119,   63-69

7、Xiaoru Zhang, Ruijuan Li, Yuanyuan Chen, Shusheng Zhang,*Wenshuang Wang, and   Fuchuan Li*, Applying DNA rolling circle amplification in fluorescence   imaging of cell surface glycans labeled by a metabolic method, Chem.   Sci.,2016,7,6182–6189.(IF 9.144)

8、X. R. Zhang, Y. Zhang, F. T. Chen, Y. Li, and S. S. Zhang. Visual detection   of single-nucleotide polymorphisms and DNA methyltransferase based on   cation-exchange of CuS nanoparticles and click chemistry of functionalized   gold nanoparticles, Chem. Commun., 2016, 52, 13261-13264.（

9、Ying Li, Chuanfeng Yu, Huixia   Han, Caisheng Zhao, Xiaoru Zhang*, Sensitive SERS detection of DNA   methyltransferase by target triggering primer generation-based multiple   signal amplification strategy, Biosensors and Bioelectronics 2016, 81,   111–116.

10、Xiaoru Zhang, Hongxia Liu, Ruijuan Li, Ningbo Zhang, Ying Xiong, Shuyan Niu.   Chemiluminescence detection of DNA/microRNA based on cation-exchange of CuS   nanoparticles and rolling circle amplification, Chem. Commun.,2015,51,   6952-6955. （IF   6.834）

11、Wenshuang Wang, Naihan Han,   Ruijuan Li, Wenjun Han, Xiaoru Zhang*, Fuchuan Li*, Supercharged   Fluorescent Protein as a Versatile Probe for the Detection of   Glycosaminoglycansin Vitro andin Vivo, Anal. Chem.2015,   87, 9302−93076

12、Xiaoru Zhang, Jiao Chen, Hongxia Liu, Shusheng Zhang. Quartz crystal   microbalance detection of protein amplified by nicked circling, rolling   circle amplification and biocatalytic precipitation, Biosensors and   Bioelectronics 65 (2015) 341–345.