性别

 男

 出生年月

 1995.03

 职称

 副教授

 学历（学位）

 博士研究生（博士）

 所属院系

 化学与分子工程学院

 导师类别

 硕士生导师

 招生专业

 分析化学，应用化学，化学工程

 研究方向

 光/电化学传感分析，纳米材料

 联系方式

  songxianzhen@qust.edu.cn

个人简历（包括近期科研项目）

宋先震，男，中共党员，博士，副教授，硕士生导师。2023年6月于济南大学获工学博士学位，主要研究方向为光/电化学传感分析，纳米材料可控制备。以第一/通讯作者在Chem. Sci., Anal. Chem., Biosens. Bioelectron, ACS Sens.等国际高水平期刊上发表SCI一区论文30余篇；获多项国家授权发明专利；主持国家自然科学基金青年基金1项，山东省自然科学基金青年基金1项；指导学生获批国家级大学生创新训练项目1项，全国大学生生命科学竞赛国家二等奖1项、三等奖1项。

承担教学课程

《大学化学》，《物理化学实验》（本科生）

主持科研项目

国家自然科学基金青年基金（22404090），2025-2027，30万元

山东省自然科学基金青年基金1项（ZR2024QB064），2025-2027，12万元

代表性论文

1. Xianzhen Song, Xiaojian Li, Dong Wei, Rui Feng, Tao Yan, Yaoguang Wang, Xiang Ren, Bin Du, Hongmin Ma,* Qin Wei. CuS as co-reaction accelerator in PTCA-K2S2O8 system for enhancing electrochemiluminescence behavior of PTCA and its application in detection of amyloid-β protein. Biosensors and Bioelectronics, 2019, 126, 222-229.

2. Xianzhen Song, Lu Zhao, Chuannan Luo, Xiang Ren, Lei Yang,* Qin Wei.* Peptide-Based Biosensor with a Luminescent Copper-Based Metal-Organic Framework as an Electrochemiluminescence Emitter for Trypsin Assay. Analytical Chemistry, 2021, 93, 9704-9710.

3. Xianzhen Song, Lu Zhao, Xiang Ren, Tao Feng, Hongmin Ma, Dan Wu, Yuyang Li,* Chuannan Luo, Qin Wei. Highly Efficient PTCA/Co3O4/CuO/S2O82– Ternary Electrochemiluminescence System Combined with a Portable Chip for Bioanalysis. ACS Sensors, 2022, 7, 2273-2280.

4. Xianzhen Song, Xiang Ren, Wei Zhao, Lu Zhao, Shoufeng Wang, Chuannan Luo, Yuyang Li,* Qin Wei.* A Portable Microfluidic-Based Electrochemiluminescence Sensor for Trace Detection of Trenbolone in Natural Water. Analytical Chemistry, 2022, 94, 12531-12537.

5. Xianzhen Song, Lu Zhao, Nuo Zhang, Lei Liu, Xiang Ren, Hongmin Ma, Chuannan Luo, Yuyang Li,* Qin Wei.* Zinc-Based Metal-Organic Framework with MLCT Properties as an Efficient Electrochemiluminescence Probe for Trace Detection of Trenbolone. Analytical Chemistry, 2022, 94, 14054- 14060.

6. Xianzhen Song, Lu Zhao, Nuo Zhang, Lei Liu, Xiang Ren, Hongmin Ma, Xuan Kuang, Yuyang Li,* Chuannan Luo,* Qin Wei.* Ultrasensitive Electrochemiluminescence Biosensor with Silver Nanoclusters as a Novel Signal Probe and α-Fe2O3-Pt as an Efficient Co-reaction Accelerator for Procalcitonin Immunoassay. Analytical Chemistry, 2023, 95, 1582-1588.

7. Yan Ding, Minghao Zhang, Mengli Ding, Xiaoting Ji, Xianzhen Song,* Caifeng Ding.* Ultrasensitive Electrochemical Biosensor Based on Efficient PDA-APDMAO Antifouling Interface and Dual-Signal Ratio Strategy for Trace Detection of Alpha-Fetoprotein in Human Serum. Analytical Chemistry, 2024, 96, 14108- 14115.

8. Mengli Ding, Zhenjie Xu, Yan Ding, Xianzhen Song,* Caifeng Ding.* High-Efficiency Electrochemiluminescence Biosensor with Antifouling and Antibacterial Functions for Sensitive and Accurate Analysis of Chloramphenicol in Seawater. Analytical Chemistry, 2025, 97, 2335-2342.

9. Qiongwei Wu, Fan Geng, Chengcheng Liu, Jia Wang, Xianzhen Song,* Caifeng Ding.* Ratiometric electrochemiluminescence biosensor based on red blood cell membrane as an efficient antifouling interface for ultrasensitive analysis of circulating tumor cells in human serum. Biosensors and Bioelectronics, 2025, 278, 117358.

10. Qiongwei Wu, Zhengjun Dong, Fan Geng, Jia Wang, Xianzhen Song,* Caifeng Ding.* Electrochemiluminescence Biosensor Based on an Efficient Antifouling Cell Membrane Hydrogel for the Direct Detection of Alkaline Phosphatase in Human Serum and Cell Lysate. Analytical Chemistry, 2025, 97, 11090-11098.

11. Lu Zhao, Zhenjie Xu, Xianzhen Song,* Caifeng Ding,* Huangxian Ju.* Self-supplying coreactant radical and structural distortion induced by carbonate ligand in metal-organic framework for anomalous deep-red self-electrochemiluminescence. Chemical Science, 2025, 16, 12493-12498.

12. Jia Wang, Zhenjie Xu, Qiongwei Wu, Wenxin Qu, Shuting Lv, Panting Chen, Gaopeng Zhang, Lu Zhao, Xianzhen Song,* Caifeng Ding.* Ultrasensitive Biosensor Based on Efficient Antifouling Interface and Dual Signal Amplification Strategy for Trace Detection of Thrombin in Serum. Analytical Chemistry, 2025, 97, 16957-16965.

13. Gaopeng Zhang, Lu Zhao, Xianzhen Song,* Caifeng Ding.* A Dual-Functional Signal “On-Off-On” Biosensor Based on Coordination-Induced Enhancement and Interface Antifouling for Trace Analysis of Alpha-Fetoprotein in Serum. Analytical Chemistry, 2025, 97, 23488-23495.

14. Wenxin Qu, Lu Zhao, Xianzhen Song,* Caifeng Ding.* Strong Self-Off Biosensor Based on Proximity-Induced DNA Strand Displacement Triggered Controlled Release for Dual-Mode Sensitive Analysis of Neuron Specific Enolase. Analytical Chemistry, 2026, 98, 1470-1479.

15. Sijia Yu, Zhen Zhao, Lu Zhao, Xianzhen Song,* Caifeng Ding.* Efficient sensing platform based on multifunctional hydrogel with antifouling, antibacterial and luminescent properties for dual-mode monitoring of okadaic acid in seawater. Chemical Engineering Journal, 2026, 531, 174087.

国家发明专利

1. 宋先震，丁彩凤，赵璐，耿帆；一种基于双重导电防污水凝胶的电化学生物传感器的构建方法和应用；ZL202411255771.5

2. 宋先震，丁彩凤，赵璐，吴琼唯；一种基于细胞膜水凝胶抗污界面的电化学发光生物传感器的构建方法和应用；ZL202510454833.3

3. 宋先震，丁彩凤，赵璐，曲文鑫；一种具有自催化增强和界面抗污双功能的生物传感器的构建方法和应用；ZL202510583644.6